Women with breast cancer who have inherited mutations in the BRCA1 or BRCA2 genes are more likely to develop breast cancer later in life in the opposite (contralateral) breast. German researchers have estimated the risk of contralateral breast cancer is related to the woman’s age when she was first diagnosed and whether she has inherited a mutation in either BRCA1 or BRCA2 genes.
05/11/2009
bioMérieux has signed an agreement with GlaxoSmithKline to develop a predictive test to help clinicians select the most appropriate treatment for breast cancer patients.
18/11/2009
Overdiagnosis of invasive breast cancer in NSW could be as high as 29% say University of Sydney researchers, suggesting that some women undergo unnecessary treatment.
17/11/2009
FURTHER to its work with the University of Pittsburgh, PGxHealth has announced its research collaboration with the Dana-Farber Cancer Institute (DCFI) to validate the use of genetic variants in Fc gamma receptors (FCGRs), in predicting response to trastuzumab (Herceptin) therapy in patients with breast cancer.
21/05/2009
Women with HER2-positive breast tumours (ie. tumours that produce too much of the HER2 protein) that are 1cm or smaller have a higher risk of their disease returning within 5 years than women with similarly small HER2-negative tumours. This finding from two retrospective studies published in the Journal of Clinical Oncology this month may shed some light on whether women with early stage, HER2-positive tumours should receive post-surgical (adjuvant) treatment.
05/11/2009
BREASTSCREEN Australia has voiced its concern over the use of imaging services promising pain-free breast cancer screening without radiation.
07/08/2009
AUSTRALIAN cancer experts have agreed women should not undergo testing for ovarian cancer unless they are experiencing signs or symptoms of the disease.
06/10/2009
A RESEARCHER with the University of Missouri is developing a device to analyse breath or urine samples to detect breast cancer, lung cancer, diabetes or asthma.
20/03/2009
Merck has begun a Phase III study of the therapeutic cancer vaccine Stimuvax (BLP25 liposome vaccine) in Asian patients with advanced non-small cell lung cancer (NSCLC). The study will investigate if Stimuvax can extend overall survival in Asian patients with unresectable stage III NSCLC.
14/12/2009
Researchers have shown that autoantibodies targeting abnormal glycoproteins produced by tumours may serve as biomarkers to detect cancer earlier.
25/02/2010
Roche has announced the results of a phase III trial investigating the use of Avastin (bevacizumab) in combination with docetaxel chemotherapy and prednisone in men with late stage prostate cancer (hormone-refractory / HRPC). The study, known as CALGB 90401, did not meet its primary objective of extending overall survival compared to chemotherapy and prednisone alone.
18/03/2010
A STUDY released by the Translational Genomics Research Institute (TGen) has claimed cancer patients are able to survive longer under treatments based on their individual genetic profiles.
21/04/2009
A RESEARCHER from Purdue University has developed probes which can help pinpoint the location of tumours and might one day be able to directly attack cancer cells.
18/03/2009
A Translational Genomics Research Institute (TGen) team has formed a partnership with Scottsdale Healthcare to conduct the first clinical trials for a drug, NMS-1286937, designed to halt cell division.
15/12/2009
Australian researchers are members of an international consortium entering a new era of personalised medicine for cancer patients.
03/05/2010
TGen Drug Development (TD2) in the US and the Institut Paoli-Calmettes (IPC) in France have formed a partnership. The arrangement aims to speed up these not-for-profit organisations' research discoveries and their introduction of new drugs into clinical trials for cancer patients.
19/11/2009
Australian researchers at the Children’s Medical Research Institute (CMRI), Sydney, has lead to the development of a test for approximately 15% of all cancers, including some of the most aggressive and potentially lethal.
23/11/2009